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The PACS2/CPT1A/DHODH signaling pathway may be involved in ferroptosis in diabetic cardiomyopathy by regulating mitochondrial function in cardiomyocytes [102]
Curcumol exhibits anti-inflammatory properties by interfering with the JNK-mediated AP-1 pathway in lipopolysaccharide-activated RAW264
The first line of defense against superoxide is the presence of a specific member of the family of metalloenzymes called superoxide dismutases (SODs), MnSOD or SOD2, specifically located in the mitochondrial matrix, which catalyzes the dismutation of superoxide anion into H 2 O 2 as shown in Figure 2
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